Control of Risks in Work with Biological Agents

Book : Control of Risks in Work with Biological Agents

Author : * E.Radek

Language : English

Library : Health-Safety-Environment

Publish Place : Germany

ISBN : 92-843-1098-9

ISSN : 1015-8022

Volume : 1

Publish Date : January 1997

Publisher : The International Social Security Association (ISSA)

Book Type : Book

Book Number : 1246

INDEX

Introduction .......................................................................... 11
Biological agents.................................................................. 12
Biology and molecular biology............................................ 21
Principles of biology and molecular biology........................ 22
Historical development of molecular biology ...................... 27
The cell:
the smallest viable component of all life forms.................... 30
The bacterium Eschehchia coli:
its chromosome, its plasmids.............................................. 33
The molecules of life:
DNA, RNA, proteins............................................................ 35
The replication of DNA........................................................ 44
From DNA to protein:
Mechanism of protein biosynthesis .................................... 45
Biotechnology ...................................................................... 53
Definition ............................................................................ 53
History and products .......................................................... 55
Modern (new) biotechnology .............................................. 59
Definition ............................................................................ 59
Fundamentals of genetic engineering ................................ 63
Spheres of application of modern biotechnology................ 69
Food production.............................................................. 69
Environment.................................................................... 69
Chemistry........................................................................ 70
Health.............................................................................. 70
Protein factors ............................................................ 71
Antihaemophilic Factor VIII ........................................ 74
Contribution of modern biotechnology
to fundamental research .................................................... 77
Infection and defence against infection.............................. 78
Application of hybridoma technology ................................ 85
Monoclonal antibodies in diagnosis and therapy ................ 88
Safety plan for the handling of biological agents.............. 91
Further reading ....................................................................101
Glossary ................................................................................104
Index ......................................................................................117
ISSA publications ................................................................ 12