Standardization of Procedures for the Study of Glucose-6-Phosphate Dehydrogenase

Book : Standardization of Procedures for the Study of Glucose-6-Phosphate Dehydrogenase

Language : English

Library : Social Phsician

Publish Place : Geneva

Volume : 366

Publish Date : 00 1967

Publisher : World Health Organization WHO

Book Type : Report

Book Number : 3407

INDEX


CONTENTS

1. Introduction.....................
2. Clinical manifestations associated with variants of G6PD . .
3. Criteria for the identification of various G6PD mutants .
4. Nomenclature.....................
5. Variants.......................
6. Geographical distribution ...............
7. Reference centres...................
8. Shipment and storage of blood samples.........
9. Recommendations...................
Annex 1. The effect of drugs on G6PD-deficient red cells . . Annex 2. Standardized method for G6PD assay of haemolysates
Annex 3. Summary of screening methods for G6PD deficiency in hemizygous males..............
Annex 4. Screening procedures :
A. BCB dye test...............
B. Methaemoglobin reduction test .......
C. MTT-linked spot test............
Annex 5. Electrophoretic characterization of G6PD variants .
Annex 6. Partial purification of human red cell G6PD . . .
Annex 7. Michaelis constants (Km's)...........
Annex 8 Thermostability studies..............
Annex 9. Classification of G6PD variants by certainty of distinctiveness.................
Annex 10. Geographical distribution of G6PD deficiency . .