World Health Organization Technical Report Series Viral Hepatisis
INDEXCONTENTSIntroduction Terminology Terminology of the antigen Terminology of the disease Viral hepatitis type A Attempts to identify hepatitis type A agent(s) by immunological methods Tissue culture studies Transmission of hepatitis type A to human volımteers Animal studies Electron microscopic studies Viral hepatitis type B Distribution and prevalence Incubation period Modes of transmission Hepatitis type B and medical çare Changing patterns of infection in certain developed countries Genetic factors Subtypes of hepatitis B antigen and their significance Immunopathology Chronic liver disease in Africa and Asia Liver celi carcinoma Extrahepatic lesions Detection and measurement of hepatitis B antigen and antibody Immunodiffusion Counter-immunoelectrophoresis Complement fixation Immune adherence Latex agglutination Passive haemagglutination and passive-haemagglutination inhibition Radioimmunoassay Immune electron microscopy Other techniques Methods for subtyping Other antigen-antibody systems Hepatitis B and blood transfusion services The prevalence of hepatitis B antigen in blood donors Hepatitis B antigen in blood and blood derivatives Use of donors with clinical evidence of prior hepatitis infection..... Post-transfusion hepatitis Management of blood donors positive for hepatitis B antigen Safety in blood transfusion laboratories Other special risk groups Maintenance haemodialysis Entry of the hepatitis virüs into dialysis or transplant units....... Spread of infection from patients to staff CONTENTS Introduction Terminology Terminology of the antigen Terminology of the disease Viral hepatitis type A Attempts to identify hepatitis type A agent(s) by immunological methods. Tissue culture studies Transmission of hepatitis type A to human volımteers Animal studies Electron microscopic studies Viral hepatitis type B Distribution and prevalence Incubation period Modes of transmission Hepatitis type B and medical çare Changing patterns of infection in certain developed countries Genetic factors Subtypes of hepatitis B antigen and their significance Immunopathology Chronic liver disease in Africa and Asia Liver celi carcinoma Extrahepatic lesions Detection and measurement of hepatitis B antigen and antibody Immunodiffusion Counter-immunoelectrophoresis Complement fixation Immune adherence Latex agglutination Passive haemagglutination and passive-haemagglutination inhibition Radioimmunoassay Immune electron microscopy Other techniques Methods for subtyping Other antigen-antibody systems Hepatitis B and blood transfusion services The prevalence of hepatitis B antigen in blood donors Hepatitis B antigen in blood and blood derivatives Use of donors with clinical evidence of prior hepatitis infection Post-transfusion hepatitis Management of blood donors positive for hepatitis B antigen Safety in blood transfusion laboratories Other special risk groups Maintenance haemodialysis Entry of the hepatitis virüs into dialysis or transplant units Spread of infection from patients to staff
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